The recent availibility of the reference data sets such as HapMap enabled us to empirically measure the power of an association study design by leveraging the correlation structure between SNPs. Association study design server efficiently designs a study to maximize statistical power given a genetic region of interest, by quickly aproximating the power of each candidate design. Along with the design, this server accurately measures the power of the design by an empirical simulation described in deBakker et al. , and gives the estimated confidence interval of the power estimate.

If you would like to design a whole-genome tag set, empirically measure the power of commercial whole-genome high-throughput products, or have any question, please contact Buhm Han. This is the joint work of Han B, Kang H, Seo M, Zaitlen N, Eskin E.

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